PROTECTIVE EFFECT OF TROPICAL FRUIT JUICE ON HISTOPATHOLOGICAL IMAGE OF RATS LUNG EXPOSED TO CIGARETTE SMOKE

novi febrianti, Irfan Yunianto, Muhammad Ilham

Abstract


Indonesia is a tropical country that has diversity of fruit. Fruit contain an array of antioxidant substances that give benefit for human health. This research purpose is to analyse the protective effect of antioxidant-rich tropical fruits juice on the lung of Wistar rats that exposed to cigarette smoke. Adult male Wistar rats (n 35) were divided into five groups of seven each, as follows: control group; cigarrette smoke group; cigarette strawbery,papaya juice; cigarette+strawbery,red guava juice; cigarette+strawbery, apple juice. Rats exposed to cigarette smoke 20 minutes/day for 40 days. Three ml of mixed fruit juice was given orally one hour after exposed. We analyse the structural damage of alveolus lumen and membrane, along with connection between alveolus. The results show that the structural damage of alveolus lumen and connection between alveolus of all fruit juice groups were significantly decrease (P<0,05) compared with cigarette smoke without fruit juice group. Strawbery & apple juice shows the best protective effect on the lung of Wistar rats that exposed to cigarette smoke.

Full Text:

PDF

References


Akdemir f. N. E., Ilhami G., Berna K., Recep. 2016. Quercetin Protects Rat Skeletal Muscle From Ischemia Reperfusion Injuri. Journal Of Enzyme Inhibition and Madicinal Chemistry. ISSN: 1475-6366.

Febrianti, N., I. Yunianto, R. Dhaniaputri. 2015. Laporan Akhir Penelitian Hibah Bersaing. Yogyakarta: Universitas Ahmad Dahlan.

Febrianti, N., I. Yunianto, R. Dhaniaputri. 2016. “Kandungan Antioksidan Asam Askorbat Pada Buah-Buahan Tropis”. Bio Wallacea Jurnal Ilmiah Ilmu Biologi. Vol. 2, No. 1, Januari 2016, 1-5.

Imam, D. & Juwono.2006. PengaruhPemberian Jus BuahTomat (Lycopersicumesculentum Mill) TerhadapMotilitas Spermatozoa MencitBalb/c Jantan yang DiberiPaparan Asap Rokok.KaryaTulisIlmiah. FakultasKedokteranUniversitasDiponegoro, Semarang.

Marianti, A. 2009. Aktivitas Antioksidan Jus Tomat pada Pencegahan Kerusakan Jaringan Paru-Paru Mencit yang Dipapar Asap Rokok. Biosantifika. Volume. 1 no. 1. Halaman 1-10.

Shraideh, Z.A & H.N. Najjar, 2011, Histological changes in tissues of trachea and lung alveoli ofalbino rats exposed to the smoke of two types of narghele tobacco products, Jourdan Journal of Biological Sciences 4 (4) 219-224.

Widayati, R. & N. Febrianti, Pengaruh Jus Buah Pepaya terhadap Gambaran Histopatologi Pulmo Tikus Putih yang Dipapar Asap Rokok, Skripsi, Universitas Ahmad Dahlan

Widodo, E., B.P. Priosoeryanto, S. Estuningsih, D.R. Agungpriyono, R. Utji, 2007, Effect of Glove cigarette exposure on white rat: special emphasis on the histopathology of respiratory tract, Med. J. Indonesia 16 (4) 212-218.

World Health Organization, 2009, World Health Statistics 2008, World Health Organization.


Refbacks

  • There are currently no refbacks.

Article Metrics

Abstract view : 33 times
PDF - 34 times